The Rocket Isotopes
Solutions

Rocket Isotopes has already set in place the resources and know-how for the manufacturing of one of the most promising isotopes used in RLT Medicine

Rocket Isotopes Competitive Advantage

Rocket Isotopes has already secured access to key resources for RLT manufacturing, getting ahead of the market

Rocket Isotopes builds on key processes and a leading science team to manufacture cutting-edge radioligand therapies

Established In-house purification process

The Rocket Isotopes team has developed an in-house semi-automated purification process that offers high-purity Tb-161.

PIONEERING Tb-161 DEVELOPMENT

The scientific team of Rocket Isotopes has been at the forefront of Tb-161 development, creating an unparalleled edge in terms of manufacturing process set-up.

In-house purification

Established an in-house semi-automated procedure to get Tb-161, with the potential of scaling up for commercial supply.

Excellent Quality

High purity of Tb-161 makes it suitable for radiolabeling at high specific activities.

while having established complete supply chain control

Rocket Isotopes is uniquely positioned to enable a reliable supply of Tb-161 to effectively enable manufacturing of radioligand therapies developed by Torpedo Pharmaceuticals

Why Tb-161?

Tb-161 is a viable competitor to Lu-177, the gold standard isotope used in the most commercially successful RLT therapy to date

  • FDA-approved in 2022, Pluvicto (Novartis) achieved blockbuster status 18 months post launch
  • $980M sales in 2023 and $1.39B in 2024 (+42% YoY growth) with peak potential projected at over $6B annually

Tb-161 is positioned to surpass Lu-177

  • Developed by scientific leaders, Terbium-161 is a radioisotope that emits both beta-minus particles and Auger and conversion electrons
  • Unique properties of Tb-161 contribute to superiority over Lu-177
  • In pre-clinical studies 161Tb-PSMA has demonstrated meaningful advantages over 177Lu-PSMA across all endpoints in preclinical studies

Tb-161 is the main isotope in sister company Torpedo’s flagship therapy

  • The relationship between Rocket Isotopes and Torpedo provides the perfect opportunity to leverage synergies between the manufacturing and product side, while optimizing the entire supply chain